Hydroxybenzoic acid - Wikipedia. Hydroxybenzoic acid. Names. IUPAC name. Hydroxybenzoic acid. Other names. p- Hydroxybenzoic acidpara- Hydroxybenzoic acid. PHBA4- hydroxybenzoate.

Identifiers. Ch. EBIChem. Spider. Drug. Bank. ECHA Info. Card. 10. EC Number. 20. 2- 8. KEGGIn. Ch. I=1. S/C7.

H6. O3/c. 8- 6- 3- 1- 5(2- 4- 6)7(9)1. H,(H,9,1. 0) YKey: FJKROLUGYXJWQN- UHFFFAOYSA- N YIn. Ch. I=1/C7. H6. O3/c. H,(H,9,1. 0)Key: FJKROLUGYXJWQN- UHFFFAOYAQO=C(O)c.

4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline. Fruit and Nut Plants from around the world. Check out our Papaya Seed Page for Papaya ( carica) varieties from around the world.

O)cc. 1c. 1cc(ccc. C(=O)O)OProperties. C7. H6. O3. Molar mass. Appearancewhite crystalline.

Odorodorless. Density. Melting point. 21. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone. Hydroxybenzoic acid is primarily known as the basis for the preparation of its esters, known as parabens, which are used as preservatives in cosmetics and some ophthalmic solutions. It is isomeric with 2- hydroxybenzoic acid, known as salicylic acid, a precursor to aspirin.

Natural occurrences. It is also found in Spongiochloris spongiosa, a freshwater green alga.

Structure, properties, spectra, suppliers and links for: Palmitic acid, 57-10-3. Structure, properties, spectra, suppliers and links for: Hexanal, 66-25-1.

The compound is also found in Ganoderma lucidum, a medicinal mushroom with the longest record of use. Cryptanaerobacter phenolicus is a bacterium species that produces benzoate from phenol via 4- hydroxybenzoate. This enzyme catalyses the first step in ubiquinone biosynthesis in Escherichia coli and other Gram- negative bacteria. Benzoate 4- monooxygenase is an enzyme that utilizes benzoate, NADPH, H+ and O2 to produce 4- hydroxybenzoate, NADP+ and H2.

O. This enzyme can be found in Aspergillus niger. As an intermediate. This enzyme participates in 2,4- dichlorobenzoate degradation in Pseudomonas putida. The enzyme 4- hydroxybenzaldehyde dehydrogenase uses 4- hydroxybenzaldehyde, NAD+ and H2.

O to produce 4- hydroxybenzoate, NADH and H+. This enzyme participates in toluene and xylene degradation in bacteria such as Pseudomonas mendocina. It is also found in carrots (Daucus carota). The enzyme that 2,4'- dihydroxyacetophenone dioxygenase transforms 2,4'- dihydroxyacetophenone and O2 into 4- hydroxybenzoate and formate.

This enzyme participates in bisphenol A degradation. It can be found in Alcaligenes sp. The enzyme 4- chlorobenzoate dehalogenase uses 4- chlorobenzoate and H2. O to produce 4- hydroxybenzoate and chloride. It can be found in pseudomonas sp.

The enzyme 4- hydroxybenzoyl- Co. A thioesterase utilizes 4- hydroxybenzoyl- Co. A and H2. O to produce 4- hydroxybenzoate and Co. A. This enzyme participates in 2,4- dichlorobenzoate degradation. It can be found in Pseudomonas sp. The enzyme 4- hydroxybenzoate polyprenyltransferase uses a polyprenyl diphosphate and 4- hydroxybenzoate to produce diphosphate and 4- hydroxy- 3- polyprenylbenzoate.

This enzyme participates in ubiquinone biosynthesis. The enzyme 4- hydroxybenzoate geranyltransferase utilizes geranyl diphosphate and 4- hydroxybenzoate to produce 3- geranyl- 4- hydroxybenzoate and diphosphate. Biosynthetically, alkannin is produced in plants from the intermediates 4- hydroxybenzoic acid and geranyl pyrophosphate. This enzyme is involved in shikonin biosynthesis. It can be found in Lithospermum erythrorhizon. The enzyme 3- hydroxybenzoate—Co. How To Unlock The Necromancer In Gauntlet Slayer Edition Characters. A ligase uses ATP, 3- hydroxybenzoate and Co.

A to produce AMP, diphosphate and 3- hydroxybenzoyl- Co. A. The enzyme works equally well with 4- hydroxybenzoate. It can be found in Thauera aromatica.

Biodegradation. This enzyme participates in 2,4- dichlorobenzoate degradation. It can be found in Candida parapsilosis. The enzyme 4- hydroxybenzoate 3- monooxygenase transforms 4- hydroxybenzoate, NADPH, H+ and O2 into protocatechuate, NADP+ and H2. O. This enzyme participates in benzoate degradation via hydroxylation and 2,4- dichlorobenzoate degradation. It can be found in Pseudomonas putida and Pseudomonas fluorescens.

The enzyme 4- hydroxybenzoate 3- monooxygenase (NAD(P)H) utilizes 4- hydroxybenzoate, NADH, NADPH, H+ and O2 to produce 3,4- dihydroxybenzoate (protocatechuic acid), NAD+, NADP+ and H2. O. This enzyme participates in benzoate degradation via hydroxylation and 2,4- dichlorobenzoate degradation. It can be found in Corynebacterium cyclohexanicum and in Pseudomonas sp. The enzyme 4- hydroxybenzoate decarboxylase uses 4- hydroxybenzoate to produce phenol and CO2. This enzyme participates in benzoate degradation via coa ligation.

It can be found in Klebsiella aerogenes (Aerobacter aerogenes). The enzyme 4- hydroxybenzoate—Co. A ligase transforms ATP, 4- hydroxybenzoate and Co. A to produce AMP, diphosphate and 4- hydroxybenzoyl- Co. A. This enzyme participates in benzoate degradation via coa ligation. It can be found in Rhodopseudomonas palustris.

Lecythophora hoffmannii is a plant pathogen that commonly inhabits fertile soil. It is known to metabolize aromatic compounds of low molecular weight, such as p- hydroxybenzoic acid. Glycosylation. It can be found in the pollen of Pinus densiflora. Chemistry. Chemically it is an aromatic polyester produced by the polycondensation of 4- hydroxybenzoic acid and 6- hydroxynaphthalene- 2- carboxylic acid. Dihydroxybenzophenone is generally prepared by the rearrangement of p- hydroxyphenylbenzoate. Alternatively, p- hydroxybenzoic acid can be converted to p- acetoxybenzoyl chloride. This acid chloride reacts with phenol to give, after deacetylation, 4,4'- dihydroxybenzophenone.

Examples of drugs made from PHBA include: 1) Nifuroxazide, 2) Orthocaine, 3) Ormeloxifene & 4) Proxymetacaine. Bioactivity and safety. The LD5. 0 is 2. 20. International Programme on Chemical Safety (IPCS). Retrieved 1. 0 January 2.

Pierre Juteau, Val. Profiling C6–C3 and C6–C1 phenolic metabolites in Cocos nucifera. Gargi Dey, Moumita Chakraborty and Adinpunya Mitra, Journal of Plant Physiology, Volume 1.

Issue 4, 2. 2 April 2. Pages 3. 75- 3. 81 doi: 1.

Catechin metabolites after intake of green tea infusions. Simonetti, C. Brusamolino, P.

Morazzoni and E. Bombardelli, Bio. Factors, 1. 99. 8, Volume 8, Issue 1- 2, pp. Comparison of Phenolic Acids and Flavan- 3- ols During Wine Fermentation of Grapes with Different Harvest Times. Rong- Rong Tian, Qiu- Hong Pan, Ji- Cheng Zhan, Jing- Ming Li, Si- Bao Wan, Qing- Hua Zhang and Wei- Dong Huang, Molecules, 2. Pacheco- Palencia LA, Mertens- Talcott S, Talcott ST (Jun 2. J Agric Food Chem.

PMID 1. 85. 22. 40. Phytochemical Analysis. Cate (1. 94. 3). 3. Lewis, R. J. Dangerous Properties of Industrial Materials. New York, NY: Van Nostrand Reinhold. Khetan (2. 3 May 2.

Endocrine Disruptors in the Environment. ISBN 9. 78- 1- 1. J Appl Toxicol. 2. PMID 1. 60. 21. 68. Holistic Beauty from the Inside Out: Your Complete Guide to Natural Health, Nutrition, and Skincare. Seven Stories Press.

ISBN 9. 78- 1- 6. PMID 9. 41. 78. 43. OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay. OECD Publishing. ISBN 9.

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